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- The New York Yankees don home uniforms with pinstripes on them for the very first time. New York lost the game, the season opener, to the Boston Red Sox, 5-3.
- Carl Yastrzemski makes his Major League debut for the Boston Red Sox against the Kansas City Athletics. He went 1-for-5.
- Rod Carew made his Major League debut with the Minnesota Twins, going 2 for 4 against the Baltimore Orioles.
- Bret Saberhagen was born in Illinois
- Jason Varitek was born in Michigan.
- Trot Nixon was born in North Carolina.
- Mark Teixeira was born in Maryland